CALCULATION OF THE INFLUENCE OF THE LEVEL OF HOMOZYGOSITY AND GENOMIC INBREEDING ON THE EXTERIOR TRAITS OF DAIRY CATTLE PRODUCTIVITY BY VARIANCE ANALYSIS
Abstract and keywords
Abstract:
The aim of this study is to evaluate the influence of the level of homozygosity (Ca) and genomic inbreeding (FROH) on conformation traits using analysis of variance. To assess the influence of FROH, data on SNP markers from 356 sires were used; FROH was then assigned to daughters (n = 42,248). FROH was calculated as the ratio of the sum of all lengths of homozygosity patterns (ROH) in million nucleotide pairs (mb) in the sire genome to the total genome size in mb for 29 bovine autosomes overlapping SNPs, expressed as a percentage. To calculate the influence of inbreeding (Fx), 355 bulls and 42,246 daughters were used, and Ca for STR markers from 342 bulls and 39,749 daughters. Fx was calculated using the Wright – Kislovsky formula, and the Ca level was calculated as the ratio of the number of homozygous loci to the total number of loci analyzed. The Soyuz Mosplem method was used for the conformation profile. For Fx, p values = 0.000 for most traits. The most pronounced effect was observed on the "A" system scores for body (R2 = 0.033) and the overall score (R2 = 0.026). According to STR, the most sensitive indicators were milk type "B" (R2 = 0.00374) and body type (R2 = 0.00369), which is confirmed by high values of the F-criterion (74.71 and 73.52, respectively). The values of the determination coefficient show a strong effect on the milk type and body; a moderate effect on the limbs (R2 = 0.00158) and udder (R2 = 0.00294) and a minimal effect on static indicators (height, cm, – R2 = 0.00028). Statistical significance is confirmed – p < 0.0001. For SNP, all indicators demonstrate p < 0.000001, R2 show that there is a strong effect on the milk type indicators (R2 = 0.030) and the overall assessment (R2 = 0.030); moderate effect on withers height (R2 = 0.023) and body height (R2 = 0.026) and minimal effect on limb position and teat parameters (R2 from 0.0001 to 0.005). The obtained results can be used to optimize the selection process and control the level of inbreeding in the herd.

Keywords:
dairy cattle, analysis of variance, dairy cattle conformation, genomic inbreeding, homozygosity, FROH, Ca, Fx
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