graduate student from 01.01.2024 to 01.01.2026
Moscow, Moscow, Russian Federation
VAK Russia 4.1.1
VAK Russia 4.1.2
VAK Russia 4.1.3
VAK Russia 4.1.4
VAK Russia 4.1.5
VAK Russia 4.2.1
VAK Russia 4.2.2
VAK Russia 4.2.3
VAK Russia 4.2.4
VAK Russia 4.2.5
VAK Russia 4.3.3
VAK Russia 4.3.5
UDC 619
UDC 636.084.415
UDC 616.36
CSCSTI 68.41
Russian Classification of Professions by Education 36.05.01
Russian Classification of Professions by Education 36.06.01
Russian Library and Bibliographic Classification 48
Russian Trade and Bibliographic Classification 5623
Russian Trade and Bibliographic Classification 562
Research Objective: To conduct a comparative analysis of age, sex, and seasonal patterns in the occurrence of hepatopathies in dogs and cats, as well as to evaluate the diagnostic efficacy of primary research methods. A retrospective cohort study was performed based on the analysis of 140 clinical cases (70 dogs and 70 cats) with verified liver diseases, selected according to clear inclusion/exclusion criteria. The diagnostic algorithm included history taking, clinical examination, blood biochemical analysis, ultrasound and radiographic studies, and in complex cases, morphological verification. Data were systematized by species, nosology, age, sex, and season of diagnosis using descriptive statistics methods. An age-related predisposition to hepatopathies was established in middle-aged and older animals (peak in the 3–6 and 6–9 years groups). A seasonal pattern was revealed: in dogs, the incidence increases in spring and early summer; in cats, in spring and autumn. Sex predisposition was less pronounced; however, the risk of developing liver pathologies was somewhat higher in females of both species, especially cats. Among |diagnostic methods, blood biochemical analysis demonstrated the highest screening efficacy and informativeness. The obtained data confirm the presence of statistically significant age and seasonal patterns in the occurrence of hepatopathies in small domestic animals. The results emphasize the importance of considering these factors in clinical practice to increase alertness and optimize the diagnostic search. Based on the identified patterns, the development of algorithmic software to support decision-making at the primary diagnostic stage is planned.
hepatopathy, dogs, cats, diagnostics, age-related predisposition, seasonality, blood biochemical analysis, ultrasound examination
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2. Connolly ED, Wu G. Characteristics of the Digestive Tract of Dogs and Cats. Adv Exp Med Biol. 2024:15-38. DOI:https://doi.org/10.1007/978-3-031-54192-6.
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8. Usenko DS, Rudenko AF, Rudenko AA. Biochemical parameters of blood serum in cats with cholangiohepatitis. Bulletin of the Ulyanovsk State Agricultural Academy. 2019;4:101-109. (In Russ.). DOI:https://doi.org/10.18286/1816-4501-2019-4-101-109. EDN: https://elibrary.ru/GBQGFS.
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10. Grechko VV, Ovchinnikov DK, Maksimyuk EV. Cytological diagnostics and surgical resection of hepatocellular carcinoma of the liver in a domestic cat. Bulletin of the Orenburg State Agrarian University. 2025;5:196-201. (In Russ.). DOI:https://doi.org/10.37670/2073-0853-2025-115-5-196-201. EDN: https://elibrary.ru/RSCBAM.
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14. Moritz AK, Köhler C, Fromme V, et al. Complications of ultrasound-guided liver biopsies in dogs and cats. Tierarztl Prax Ausg K Kleintiere Heimtiere. 2018;46(3):5-13. DOI:https://doi.org/10.15654/TPK-170183. EDN: https://elibrary.ru/ODHVHL.
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18. Lineva A, Tavčar Benković E, Kreft S. Remarkable Frequency of a History of Liver Disease in Dogs Fed Home Diets with Buckwheat. Tierarztl Prax Ausg K Kleintiere Heimtiere. 2019;47(4):242-246. DOI:https://doi.org/10.1055/a-0894-8141.
19. DeJesus AA, Penninck DG, Webster CR. Ultrasonographic evaluation of cholecystoduodenostomy sites in six cats. J Feline Med Surg. 2021;23(2):194-202. DOI:https://doi.org/10.1177/1098612X20921062. EDN: https://elibrary.ru/QYUCQJ.
20. Shchekotova AP, Bulatova IA, Paducheva SV. Liver syndromes and cytokine levels in patients with liver cirrhosis. Perm Medical Journal. 2019;36(5):27-34. (In Russ.). DOI:https://doi.org/10.17816/pmj36527-34 EDN: https://elibrary.ru/SFTYVW.
